Jay V Patankar Selected Research

Steroid 12-alpha-Hydroxylase (CYP8B1)

1/2018	Genetic ablation of Cyp8b1 preserves host metabolic function by repressing steatohepatitis and altering gut microbiota composition.
1/2018	Therapeutic modulation of the bile acid pool by Cyp8b1 knockdown protects against nonalcoholic fatty liver disease in mice.
4/2015	Loss of Cyp8b1 improves glucose homeostasis by increasing GLP-1.

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Jay V Patankar Research Topics

Disease

5	Inflammation (Inflammations) 01/2022 - 01/2018
5	Insulin Resistance 01/2018 - 03/2011
3	Colitis 12/2022 - 01/2021
3	Metabolic Diseases (Metabolic Disease) 01/2018 - 03/2011
2	Ulcerative Colitis 12/2022 - 01/2021
2	Hemorrhage 12/2022 - 01/2022
2	Fibrosis (Cirrhosis) 01/2018 - 11/2012
2	Fatty Liver 01/2018 - 01/2018
2	Liver Diseases (Liver Disease) 01/2018 - 01/2018
1	Thrombosis (Thrombus) 12/2022
1	Wounds and Injuries (Trauma) 12/2022
1	Thromboinflammation 12/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Necrosis 01/2021
1	Non-alcoholic Fatty Liver Disease 01/2018
1	Type 2 Diabetes Mellitus (MODY) 07/2016
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2016
1	Hyperglycemia 07/2016
1	Wolman Disease (Wolman's Disease) 01/2016
1	Hypercholesterolemia 10/2013
1	Atherosclerosis 10/2013
1	Atherosclerotic Plaque (Atheroma) 10/2013
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2013
1	Body Weight Changes 01/2013
1	Body Weight (Weight, Body) 01/2013
1	Obesity 03/2011
1	Hyperlipidemias (Hyperlipidemia) 03/2011

Drug/Important Bio-Agent (IBA)

4	LipidsIBA 01/2018 - 03/2011
3	Steroid 12-alpha-Hydroxylase (CYP8B1)IBA 01/2018 - 04/2015
2	CholesterolIBA 01/2018 - 03/2011
2	Bile Acids and Salts (Bile Acids)IBA 01/2018 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 07/2016 - 04/2015
2	Glucagon-Like Peptide 1 (GLP 1)IBA 11/2012 - 03/2011
1	Arginine (L-Arginine)FDA Link 12/2022
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 12/2022
1	FibrinIBA 12/2022
1	Histones (Histone)IBA 12/2022
1	Caspase 8 (Caspase-8)IBA 01/2022
1	ProstaglandinsIBA 01/2021
1	Protein Kinases (Protein Kinase)IBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	CytokinesIBA 01/2021
1	Interleukin-13IBA 01/2021
1	Dinoprostone (PGE2)FDA Link 01/2021
1	3,5- diethoxycarbonyl- 1,4- dihydrocollidineIBA 01/2018
1	Protein AggregatesIBA 01/2018
1	Cholic AcidIBA 01/2018
1	Fenofibrate (CiL)FDA LinkGeneric 01/2018
1	LigandsIBA 01/2018
1	Sterol Esterase (Hormone-Sensitive Lipase)IBA 01/2016
1	ApolipoproteinsIBA 10/2013
1	xanthohumolIBA 10/2013
1	Apolipoproteins E (ApoE)IBA 10/2013
1	Biological ProductsIBA 10/2013
1	OxysterolsIBA 02/2013
1	Succinic Acid (Succinate)IBA 01/2013
1	Adenosine Triphosphate (ATP)IBA 01/2013
1	Proteins (Proteins, Gene)FDA Link 01/2013
1	EnzymesIBA 01/2013
1	AntioxidantsIBA 01/2013
1	oil red OIBA 11/2012
1	Triglycerides (Triacylglycerol)IBA 03/2011

Therapy/Procedure

1	Remission Induction 01/2021
1	Therapeutics 01/2018